(ANSA) – ROME, NOVEMBER 08 – Those who contracted COVID-19 produce antibodies. But those who are elderly produce more. This is what emerges from a small study by the Université de Montréal published today in Scientific Reports, which analyzed the antibody response of 32 Canadian adults who tested positive in 2020 for SARS-CoV-2 and did not need hospitalization.
The patients had been recruited from the Center hospitalier of the Université Laval. Analysis of their antibody response was done 4 and 16 weeks after the diagnosis of SARS-CoV-2 by PRC test. The first finding was that antibodies continued to be present in the blood even 16 weeks after diagnosis. But what attracted the attention of the researchers was also the correlation between the antibody response and the age of the patients: those over 70 had above-average responses while under the age of 49 there were below-average antibody responses.
Antibodies produced after infection by the original strain of the virus also reacted to variants that emerged in subsequent waves – B.1.351 (Beta, South African), B.1.617.2 (Delta, Indiana) and P.1 (Gamma Brazilian) – but to a reduced extent of about 30-50%. Even in the case of the variants, however, an age-related gap was evident.
In detail, those over 70 showed responses from 15% (native strain) to 30% (variants) above the average of the overall cohort, those aged 50-59 or 60-69 years showed responses within 10 % of the mean, and those aged 18 to 49 showed responses 18% (native) to 30% (variants) below the mean.
Finally, the study showed that in a patient under the age of 49, the previous infection did not produce antibodies, but vaccination did. (HANDLE).
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Source From: Ansa
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