Scientists have discovered potential in an entirely different field of medicine in an experimental cancer drug. The tool can be a solution to the problem of obesity
Cancer drug could help fight obesity / Photo: Pixabay, Collage: Today
ADI-PEG 20 is being studied as a potential treatment for a range of cancers such as sarcoma, breast and pancreatic cancer.
: Experimental drug destroys tumors in terminally ill cancer patients
It works by destroying an amino acid in the blood (arginine), which robs cancer cells of an important source of fuel.
Research has shown that the activity of the genes responsible for the breakdown of arginine is significantly increased when the body enters a state of starvation.
The scientists decided to see if this drug could be used to mimic the effects of fasting, and they conducted experiments on mice.
They showed that the drug causes the cells to participate in the process of self-eatingcalled autophagy, in which they burn their own waste as fuel.
The drug was found to protect mice genetically engineered for obesity predisposition from gaining weight, as well as causes weight loss in obese micewho are on a diet high in fat and sugar.
In addition, he improved cholesterol levels and insulin sensitivity in rodents, reduced inflammation, and decreased liver fat accumulation.
The results of the study demonstrated the potential of the drug, but scientists note that its effectiveness can only work in the short term, since it has a protein base, and this can cause an immune response, according to newatlas.com.
We previously reported that the heart of a pig was successfully transplanted into a human for the first time. 57-year-old American David Bennett with a life-threatening disease transplanted the heart of a genetically modified pig.
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Source From: Segodnya
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