Also the immune system has his own internal clockthat the indicates when it is day: in hours of lightin fact, the cell That fight the infections caused by viruses and bacteria are much more active than the night. This was revealed by the study led by the University of Auckland, New Zealand, and published in the magazine Science Immunology.
The results open the way to the development of New drugs targeted that act precisely on the circadian clock of the immune system, in order to enhance its ability to contrast invaders. The researchers coordinated by Christopher Hall focused on neutrophils, the most abundant white blood cells of our body and the first to arrive in the sites in which a bacterial infection is presented. To be able to observe their behavior in real time, they used the zebra fishone of the most present animals in the laboratories since shares with human beings up to 70% of genes And it is transparent, therefore it allows you to directly see what happens within the body.
The researchers thus discovered that the response of the immune system result Synchronized with there light of day: in fact, neutrophils have a circadian clock, just like many other cells of our body, which warns them when it is day and increases their ability to kill bacteria. “Since neutrophils are the first immune cells to be recruited in inflammation sites – says Hall – our discovery has very large implications regarding therapeutic benefits in many inflammatory diseases”.
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