Who does work they require night shifts risks get old Very faster: the cause is inbiological watch from the muscle cellswhich comes altered by night activity and thus causes the loss Of muscle tissue and of Forcejust as it normally happens in old age. The Health consequences they can be serious, like physical disabilityincreased risk Of falls And fractures And reduction from the quality of life. This is indicated by the study conducted on zebra fish, among the organisms most studied by the geneticists, and coordinated by the King’s College of London. Published in the magazine of the National Academy of American Sciences, Pnas, Research lays the foundations for developing strategies that can improve health and workers forced to night shifts.
The researchers coordinated by Jeffrey Kelu used the zebra fishThat shares with human beings up to 70% of genesAnd Simple to study in the laboratory and is transparenttherefore allows you to observe easily also i muscles. So it emerged that the muscle cells have their own internal clock: Of Nightthis starts the degradation of defective proteins which accumulate during the day, regeneously The muscles while the body rests.
The fish with malfunctioning clock instead showed the classic signs of aging accelerated: “Although no significant differences have been observed at a younger age, such as 6 months or 1 year, i Pisces without of a functional muscle clock showed clear signs Of early aging at 2 years old, “says Kelu:” They were smallerweighed less, they swam less frequently and lower speeds. This opens the way to future therapies that could improve the aging of workers “.
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